舒芬太尼和右美托咪啶的临床麻醉及术后镇痛效果

Clinical Anesthesia and Postoperative Analgesic Effect of Sufentanil and Dexmedetomidine

目的:分析舒芬太尼和右美托咪啶的临床麻醉及术后镇痛效果。方法:选取2017年10月-2019年3月于笔者所在医院进行全身麻醉手术患者78例,采用随机数字表法分为两组,各39例。常规组术中应用芬太尼麻醉,术后应用舒芬太尼镇痛;干预组术中应用舒芬太尼麻醉,术后应用舒芬太尼和右美托咪啶镇痛,对比两组麻醉及术后镇痛效果。结果:干预组气管导管拔除时间、苏醒时间、自主呼吸恢复时间均明显短于常规组,术后2、12、24 h VAS评分均明显低于常规组(P<0.05);干预组不良反应发生率略低于常规组,差异无统计学意义(P>0.05)。结论:舒芬太尼和右美托咪啶的临床麻醉及术后镇痛效果较显著,能有效减轻术后疼痛,且安全性高,有助于缩短苏醒时间,及早拔除气管导管,可促进自主呼吸恢复。

Objective:To analyze the clinical anesthesia and postoperative analgesic effect of Sufentanil and Dexmedetomidine.Method:A total of 78 patients who underwent general anesthesia operation in our hospital from October 2017 to March 2019 were selected and divided into two groups by random number table method,39 patients in each group.The routine group received Fentanyl anesthesia during operation,Sufentanil analgesia after operation.And the intervention group received Sufentanil anesthesia during operation and Sufentanil and Dexmedetomidine analgesia after operation.The clinical anesthesia and postoperative analgesic effect of the two groups were compared.Result:The time of tracheal intubation removal,recovery and spontaneous breathing recovery in the intervention group were significantly shorter than those of the routine group,and VAS scores at 2,12 and 24 hours after operation were significantly lower than those of the routine group(P<0.05).The incidence of adverse reactions in the intervention group was slightly lower than that of the routine group,but the difference was not statistically significant(P>0.05).Conclusion:Sufentanil and Dexmedetomidine are effective in clinical anesthesia and postoperative analgesic effect,which can effectively relieve postoperative pain,and have high safety.It can shorten the recovery time,remove tracheal intubation as early as possible,and promote spontaneous breathing recovery.