东莨菪碱配伍硫酸镁在产程中的应用

Application of Scopolamine in Combination with Magnesium Sulfate in Labor Process

目的探讨东莨菪碱配伍硫酸镁在产程中的应用。方法选择2016年7月—2018年7月住院分娩产妇400例,随机均分为对照组和观察组,各200例。给予对照组安定治疗,观察组使用东莨菪碱配伍硫酸镁治疗。比较两组产妇相关临床指标、宫颈水肿消肿情况以及新生儿窒息率和第一产程时间。结果观察组的产后出血率、产钳助产率、剖宫产率、宫颈裂伤率、宫颈水肿消肿总有效率及第一产程时间明显低于对照组,观察组的自然分娩率明显高于对照组,差异均具有统计学意义(P<0.05)。观察组的新生儿窒息率(1.00%)低于对照组(3.50%),差异无统计学意义(P>0.05)。结论东莨菪碱配伍硫酸镁在产程中具有良好的应用效果,能提高自然分娩率,降低剖宫产率,有利于宫颈水肿消肿,减少新生儿窒息率及产后出血率,值得在临床上推广应用。

Objective To investigate the application effect of scopolamine in combination with magnesium sulfate in the labor process.Methods A total of 400 women who were hospitalized in our hospital from July 2016 to July 2018 were randomly divided into control group and observation group,200 cases each.The control group was given stable treatment,and the observation group was treated with scopolamine and magnesium sulfate.The maternal related clinical indicators,cervical edema and swelling,as well as neonatal asphyxia rate and first labor time were compared.Results The postpartum hemorrhage rate,the yield-producing rate,the cesarean section rate,the cervical laceration rate,the total effective rate of cervical edema and the first stage of labor were significantly lower in the observation group than in the control group.The natural delivery rate of the observation group was obvious.The difference was statistically significant(P<0.05).The neonatal asphyxia rate in the observation group was 1.00%significantly lower than that in the control group 3.50%,and there was no significant difference(P>0.05).Conclusion The combination of scopolamine and magnesium sulfate has a good application effect in the labor process,which can improve the natural delivery rate,reduce the cesarean section rate,favor cervical edema and reduce the neonatal asphyxia rate and postpartum hemorrhage rate.It is worthy of clinical application.