宫颈上皮内瘤变在宫颈LEEP术后的转归

Loop Electrosurgical Excision Procedure in the Treatmentof Cervical Intraepithelial Neoplasia

目的探讨分析宫颈上皮内瘤变(CIN)的治疗与转归。方法方便选取邵武市立医院2017年1—12月通过阴道镜及宫颈活检诊断为CIN进行宫颈LEEP术治疗的102例患者为研究对象,比较术前宫颈活检与术后病理检查结果的符合率,术后随访官颈复原情况并对其临床疗效进行回顾性分析。结果术前术后病理诊断符合率为46.6%,病理级别上升率为19.4%,病理级别下降率为32.0%。术后102例患者中(5例切缘阳性再次行LEEP术,3例行子宫+双侧输卵管切除,5例行广泛子宫切除+盆腔淋巴结清扫术),宫颈复原满意者达100.0%,治愈率为99.0%。结论LEEP是诊断和治疗CIN安全有效的方法。

Objective To investigate the treatment and prognosis of cervical intraepithelial neoplasia(CIN).Methods A total of 102 patients diagnosed as CIN by colposcopy and cervical biopsy in Shaowu municipal hospital from January to December 2017 were convenient selected and treated with cervical LEEP.The coincidence rate between preoperative cervical biopsy and postoperative pathological examination was compared.The recovery of the official neck was followed up after surgery,and the clinical efficacy was retrospectively analyzed.Results The coincidence rate of pathological diagnosis before surgery was 46.6%.The rising rate of pathological grade was 19.4%,and the falling rate of pathological grade was 32.0%.Of the 102 patients(5 patients with positive margin and LEEP,3 patients with uterus+bilateral salpingectomy,5 patients with extensive hysterectomy+pelvic lymphadenectomy),patients with satisfactory cervical recovery reached to 100.0%and cure rate was 99.0%.Conclusion LEEP is a safe and effective method for diagnosing and treating CIN.