血栓弹力图与传统凝血功能检查在颅脑损伤患者手术中的应用效果比较

Application effect comparison of the thromboelastography and traditional coagulation function in patients with craniocerebral injury

目的分析血栓弹力图和传统凝血功能检查在颅脑损伤手术患者中的应用效果。方法选取2018年1~12月我院收治的46例接受手术治疗的颅脑损伤患者作为研究对象,根据手术期间凝血功能监测方法的不同将患者分为对照组和观察组,每组各23例。对照组患者行传统凝血功能检查监测,观察组患者行血栓弹力图检查监测,比较两组患者的手术时间、出血量、输液量等各手术指标及术后情况。结果两组患者的手术时间、尿量比较,差异无统计学意义(P>0.05);观察组患者的出血量、输液量、悬浮红细胞输注量、新鲜冰冻血浆输注量、冷沉淀输注量、血小板输注量均少于对照组,差异有统计学意义(P<0.05);观察组患者术后6、24 h引流量少于对照组,差异有统计学意义(P<0.05)。结论颅脑损伤患者在手术治疗时接受血栓弹力图检查,可以对患者的凝血功能进行准确的判断,减少血液制品的输注量,对患者的治疗具有重要意义。

Objective To analyze the application effect of thromboelastography and traditional coagulation function in patients with craniocerebral injury.Methods Forty-six patients with craniocerebral injury who underwent surgery in our hospital from January to December 2018 were selected as the subjects.The patients were divided into control group and observation group according to different coagulation function monitoring methods during operation,with 23 cases in each group.The patients in the control group underwent traditional coagulation function monitoring.The patients in the observation group underwent thromboelastography monitoring.The operation time,blood loss,infusion volume and other operation indexes and postoperative status were compared between the two groups.Results There were no significant differences in the operation time and urine volume between the two groups(P>0.05).The amount of bleeding,infusion volume,suspended red blood cell transfusion,fresh frozen plasma infusion,cryoprecipitate infusion,and platelet transfusion in the observation group were less than those in the control group,and the differences were statistically significant(P<0.05).The drainage volume at 6 and 24 h after operation in the observation group were less than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Patients with craniocerebral injury undergo thromboembolic examination during surgical treatment,which can accurately judge the coagulation function of patients and reduce the infusion of blood products,which is of great significance for the treatment of patients.