头部亚低温治疗新生儿重度窒息的临床效果及预后分析

Clinical effect and prognosis of mild hypothermia of head in the treatment of neonatal severe asphyxia

目的:分析在重度窒息新生儿中应用头部亚低温治疗的效果以及对预后的影响。方法:2017年10月-2018年10月收治新生儿窒息患儿30例,分为两组,各15例。对照组实施常规治疗,干预组在常规治疗同时实施头部亚低温治疗。对比两组患儿相关功能指标水平及预后效果。结果:两组患儿治疗后相关指标水平均有所改善,但干预组天门冬氨酸氨基转移酶(AST)、肌酸激酶同工酶(CK-MB)水平明显优于对照组,差异有统计学意义(P<0.05)。干预组患儿治疗后NBNA评分及预后效果显著优于对照组,差异有统计学意义(P<0.05)。结论:实施头部亚低温治疗重度窒息新生儿能够有效改善患儿各指标水平,提高预后效果。

Objective:To explore the effect of mild hypothermia on the head and its effect on the prognosis of neonates with severe asphyxia.Methods:From October 2017 to October 2018,30 children with neonatal asphyxia were selected,and they were divided into two groups of 15 cases in each.The control group was treated with conventional treatment,the intervention group was treated with mild hypothermia of head on the basis of conventional treatment.We compared the level of related functional indexes and prognosis between the two groups.Results:After treatment,the level of relevant indicators in the two groups improved,however,AST and CK-MB data in the intervention group were significantly better than those in the control group,the difference was statistically significant(P<0.05).The NBNA score and prognosis of the intervention group were significantly better than those of the control group,the difference was statistically significant(P<0.05).Conclusion:Mild hypothermia of head in the treatment of neonatal severe asphyxia can effectively improve the level of physical indicators and improve the prognosis.