小儿咳喘宁口服液对小儿急性毛细支气管炎的临床疗效分析

Clinical efficacy of Xiaoer Kechuanning oral liquid in the treatment of children with acute bronchitis

目的:探讨小儿咳喘宁口服液对小儿急性毛细支气管炎的临床疗效。方法:回顾性分析我院160例毛细支气管炎患儿,采用随机数字表法分为对照组(n=80)和观察组(n=80)。收集并分析两组血清IL-4、IFN-γ、肺功能及症状体症的变化。结果:观察组治疗后IL-4、IFN-γ、住院时间、咳嗽痰响消失时间、干湿性啰音消失时间、症状体征体温恢复时间水平均低于对照组(P<0.05);观察组达峰容积比、达峰时间比、潮气量及呼吸比均高于对照组(P<0.05);观察组不良反应发生率低于对照组(P<0.05)。结论:中西医结合治疗小儿毛细支气管炎效果佳,可有效改善患儿炎症因子水平,值得临床进一步实践。

Objective: To explore the clinical effect of Xiaoer Kechuanning oral liquid on children with acute bronchiolitis.Methods: Data from 160 cases of bronchiolitis admitted to our hospital were retrospectively analyzed and they were divided into a control group and an observation group with 80 cases each based on a random number table method.The changes in serum IL-4, IFN-γ, lung function and symptomatic symptoms were compared between the two groups.Results: after treatment.The IL-4, IFN-γ levels, the duration of hospitalization and the time for phlegm loss, dryness and dampness and temperature recovery of symptomatic symptoms were lower or less in the observation group than the control group(P<0.05).The peak volume ratio, peak time ratio, tidal volume and respiration ratio were all higher in the observation group than the control group(P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group(P<0.05).Conclusion: The combination of Chinese and western medicine for the treatment of infantile bronchiolitis is effective, can effectively improve the level of inflammatory factors and is worthy of clinical further practice.