乳腺癌胃转移1例

One case of gastric metastasis from breast cancer

乳腺癌是女性最常见的恶性肿瘤之一,早期乳腺癌多不具备典型的症状和体征,通常是由体检或筛查发现后通过细胞或组织病理学明确诊断,并采用手术、放化疗、靶向及内分泌治疗等方法进行综合治疗,其预后受病理类型、疾病分期、分子标志物等多种因素影响。尽管早期乳腺癌经综合治疗后已成为治疗效果最佳的实体肿瘤之一,一旦出现复发转移其生存时间仍将迅速缩短。乳腺癌常见转移部位为骨骼、淋巴结、软组织及肺、脑、肝等,以胃为首发转移部位相对罕见且其临床、影像学及胃镜表现均缺乏特异性,与原发性胃癌鉴别困难。本文将报道1例乳腺浸润性小叶癌转移至胃的患者,并结合文献分析该疾病的临床特征、诊断、治疗方法及预后,以提高临床对乳腺癌胃转移的认识。

Breast cancer is one of the most common malignant tumors in women.Most early breast cancer do not have typical symptoms and signs.Cell or histopathology is used diagnose the disease after physical examination or screening and treated by comprehensive treatment methods such as surgery,chemoradiotherapy,targeting and endocrine therapy.The prognosis of breast cancer is affected by many factors,for example pathological type,stage of disease,molecular markers,and so on.Although early breast cancer has become one of the most effective solid tumors after comprehensive treatment,the survival time will be shortened rapidly once recurrence and metastasis occur.The common metastatic sites are bone,lymph node,soft tissue,lung,brain,liver,and so on.The gastric as the first site of metastasis is rela-tively rare and the clinical,imaging and endoscopic manifestations are lack of specificity,making it difficult to differen-tiate from primary gastric cancer.This paper reports a case of invasive lobular breast carcinoma with gastric metastasis and analyzes the clinical characteristics,diagnosis,treatment and prognosis of the disease combined with the literature,in order to improve the clinical understanding of gastric metastasis from breast cancer.