C反应蛋白及降钙素原检测对感染性休克患者的运用意义

Significance of detection of C-reactive protein and procalcitonin in patients with septic shock

目的对感染性休克患者进行C反应蛋白和降钙素原检测的效果进行研究。方法择选入住本院ICU的感染性休克患者40例作为研究对象,并将其分为死亡组(20例)和存活组(20例)。并对两组患者的CRP、PCT水平以及APACHEII评分进行对比分析。结果通过对比两组患者的CRP和PCT水平发现,第一天两组患者差异不大(P>0.05),但是到第二天、第四天以及最后的转出或死亡期前,死亡组的CRP和PCT水平显著较存活组高,且对比差异显著(P<0.05);并且通过对比两组患者的APACHEII评分发现,APACHEII评分正相关于PCT和CRP水平(r=0.628,P<0.01和r=0.621,P<0.01)。结论对感染性休克患者进行C反应蛋白和降钙素原检测具有较好的效果,值得推广。

Objective To investigate the effects of C-reactive protein and procalcitonin in patients with septic shock.Methods Forty patients with septic shock who were admitted to the ICU of our hospital were selected as the study subjects,and were divided into the death group(20 cases)and the survival group(20 cases).The CRP,PCT levels and APACHE II scores of the two groups were compared and analyzed.Results By comparing the CRP and PCT levels of the two groups of patients,it was found that the difference between the two groups was not significant on the first day(P>0.05),but before the next day,the fourth day and the last transfer or death period,the death group The levels of CRP and PCT were significantly higher than those in the surviving group,and the difference was significant(P<0.05).And by comparing the APACHE II scores of the two groups,the APACHE II score was positively correlated with PCT and CRP levels(r=0.628,P<0.01 and r=0.621,P<0.01).Conclusion The detection of C-reactive protein and procalcitonin in patients with septic shock has a good effect and is worthy of promotion.