中医养阴活血法在缺血性中风疾病中的临床应用

Clinical Effect of Chinese Medicine of Nourishing Yin and Promoting Blood Circulation in Ischemic Stroke

目的:探讨缺血性中风疾病的中医养阴活血治疗方式的效果。方法:选择医院2017年9月—2018年6月科室收治的84例缺血性中风病患者,按照患者入院后的自愿原则标记,将偶数号患者分为观察组,奇数号作为对照组,每组42例。对照组患者采用血栓心脉宁胶囊配合低分子右旋糖酐静脉滴注。观察组患者采用中医养阴活血法随症加减治疗方式。7 d为1个疗程,连续治疗2个疗程。观察两组临床治疗效果、临床症状积分变化,统计分析治疗前后抗凝血酶Ⅲ活性(AT-ⅢA)、抗凝血酶Ⅲ抗原(AT-ⅢAg)及神经功能(ESS量表)评分、运动功能(Fugl-Meyer)评分的变化。结果:①观察组临床总有效率为95.24%(40/42),对照组临床总有效率为73.81%(31/42),两组比较差异显著(P<0.05);②治疗后观察组症状积分与对照组比较明显降低,比较差异更加显著(P<0.05);③治疗前AT-ⅢA、AT-ⅢAg指标两组比较无变化(P>0.05),治疗后观察组抗凝指标均有明显改善(P<0.05);④治疗后观察组患者的ESS评分显著低于对照组,而Fugl-Meye评分则高于对照组(P<0.05)。结论:缺血性中风疾病应用中医中的养阴活血疗法,对于患者的临床症状具有明显的改善,同时患者的治疗效果更为显著,同时抗凝指标显著改善,是缺血性中风疾病的有效治疗方法。

Objective:To investigate the effect of nourishing Yin and promoting blood circulation TCM treatment of ischemic stroke disease.Methods:Totally 84 cases of ischemic stroke patients in our hospital from September 2017 to June 2018 were selected,in accordance with the principle of voluntary labeling of patients after admission,while the even number patients were divided into observation group,odd number patients as the control group,42 cases in each group.Patients in the control group were treated with Xueshuan Xinmaining Capsule and low molecular dextran intravenous drip.Patients in the observation group were treated with TCM Yin nourishing and blood activating therapy.7 days was a course of treatment,continuously for 2 courses.The changes of clinical therapeutic effect and clinical symptom score were observed.The changes of antithrombin Ⅲ activity(AT-ⅢA),antithrombin Ⅲ antigen(AT-ⅢAg),neurological function(ESS)and motor function(Fugl-Meyer)scores were analyzed before and after treatment.Results:The total clinical effective rate was 95.24%(40/42)in the observation group and 73.81%(31/42)in the control group.There was a significant difference between the two groups(P<0.05).After treatment,the symptom score of the observation group was significantly lower than that of the control group,and the difference was more significant(P<0.05).Thirdly,the indexes of AT-ⅢA and AT-ⅢAg before treatment were compared between the two groups without change(P>0.05).Lastly,the observation group after treatment of anticoagulation was significantly improved after treatment(P<0.05)and the ESS score of the observation group was significantly lower than that of the control group,while Fugl-Meye score was higher than that of the control group(P<0.05).In conclusion,the treatment of nourishing Yin and activating blood circulation in traditional Chinese medicine for ischemic apoplexy can improve the clinical symptoms of patients,and the therapeutic effect of patients is more remarkable.At the same time,the anticoagulant index is significantly improved.It is an effective treatment for ischemic apoplexy.