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SOX9和RUNX3在结直肠腺癌中的表达及其与临床病理因素的关系 被引量:3

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摘要 采用免疫组织化学染色法检测SOX9和RUNX3在结直肠腺癌(colorectal cancer,CRC)中的表达情况,分析其表达水平与临床病理因素的关系。结果发现,SOX9在CRC中的表达高于癌旁正常组织,差异有统计学意义(63.8%和25.4%,x^2=38.913,P<0.001);RUNX3在CRC中的表达低于癌旁正常组织,差异有统计学意义(33.8%和73.1%,x^2=40.208,P<0.001)o SOX9和RUNX3在CRC中的表达均与肿瘤的浸润深度、淋巴结转移和TNM分期有关;SOX9和RUNX3在CRC中的表达呈负相关。
出处 《中华普通外科杂志》 CSCD 北大核心 2019年第12期1083-1084,共2页 Chinese Journal of General Surgery
基金 辽宁省自然科学基金指导计划项目(201602751)。
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