改善糖尿病内皮祖细胞功能的研究进展

Research on the improving function of endothelial progenitor cells in diabetes

内皮祖细胞(EPC)为来源于骨髓及外周血中的干细胞,能定向增殖分化为内皮细胞,参与血管损伤后的修复。研究显示,改善糖尿病EPC功能,可以预防和降低糖尿病并发症的发生。追踪近年来改善EPC功能的研究进展,就其对糖尿病并发症的预防和改善作用做一综述,以期为糖尿病的治疗提供新思路。

Endothelial progenitor cells(EPC)are stem cells derived from bone marrow and peripheral blood,which could proliferate and differentiate into endothelial cells and participate in repair after tube injury.Studies have shown that the improving function of diabetic EPC could prevent and reduce the occurrence of diabetic complications.The research progress in improving the function of EPC in recent years and the improvement of function in the development of diabetes were reviewed in order to provide new ideas for the treatment of diabetes.