花生营养油对中老年SD大鼠大脑皮层单胺氧化酶活性及肝脏细胞的影响研究

Effects of peanut nutrition oil on monoamine oxidase activity and liver in cerebral cortex of SD rats

为了初步探究添加二十二碳六烯酸(DHA)藻油和花生四烯酸(AA)油脂的花生营养油的功能性,分别以不同DHA藻油和AA油脂剂量的花生营养油灌喂的中老年SD大鼠,持续饲喂8周后,检测对其大脑皮层组织中单胺氧化酶活性和肝脏细胞组织的影响。结果表明,饲喂花生营养油的对照组与饲喂普通花生调和油组相比,具有显著差异(P<0.01),含DHA藻油和AA油脂的花生营养油可显著降低中老年SD大鼠大脑皮层中的单胺氧化酶活性,有效改善中老年SD大鼠的肝脏水肿及细胞炎症等症状,减缓细胞衰亡的速度。由此推测,摄入适量的DHA和AA在一定程度上能降低老年人肝硬化和肝纤维化等疾病的风险,达到保护肝脏的作用。

To study the function of peanut nutrient oil supplemented with DHA algae oil and AA oil,SD rats were gavaged with peanut oil supplemented with different dose of DHA algae oil and AA oil,respectively the effects on monoamine oxidase activity in cerebral cortex and liver cell were examined after 8 weeks of continuous feeding.The results showed that the control group fed with peanut nutrient oil had significant difference compared with the normal peanut blending oil group(P<0.01).Peanut nutrient oil containing DHA algae oil and AA oil can significantly reduce the activity of monoamine oxidase in the cerebral cortex of SD rats,and effectively improve the symptoms of liver edema and cell inflammation in middle-aged SD rats,and slow down the rate of cell death.It can be speculated that the intake of appropriate amounts of DHA and AA can potentially reduce the risk of liver cirrhosis and fibrosis in the elderly people,and achieve the role of protecting the liver.