OSAHS患儿红细胞分布宽度及其与病情严重度的相关性研究

Study on the correlation between red blood cell distribution width and severity in children with OSAHS

目的观察阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患儿红细胞分布宽度(RDW)及其与病情严重程度的相关性。方法选取2015年7月至2018年2月在绍兴第二医院耳鼻喉科住院治疗的87例OSAHS患儿作为观察组,选取同期在该院体检中心行健康体检的87例健康儿童作为对照组,将观察组术前、术后的RDW及血红蛋白(Hb)与对照组进行比较。结果RDW在对照组、术前及术后6个月观察组分别为(13.31±0.87)%、(14.33±0.97)%和(13.44±1.03)%,对照组与术前观察组比较、术前与术后6个月观察组比较,差异均有统计学意义(P<0.05),对照组与术后6个月观察组比较,差异无统计学意义(P>0.05)。轻、中、重度OSAHS患儿术前RDW分别为(13.28±0.67)%、(14.43±0.83)%和(14.98±0.61)%,三者比较差异有统计学意义(P<0.05)。结论OSAHS患儿RDW明显升高,RDW可用于OSAHS患儿病情程度的辅助判断。

Objective To observe the relationship between red blood cell distribution width(RDW)and severity in children with obstructive sleep apnea hypopnea syndrome(OSAHS).Methods A total of 87 children with OSAHS who were hospitalized in Otolaryngology Department of Shaoxing Second Hospital from July 2015 to February 2018 were selected as the observation group.At the same time,87 children who underwent health examination in the physical examination center were selected as the control group.RDW and hemoglobin(Hb)were compared between the two groups.Results RDW in the control group,the observation group before operation and the observation group 6 months after operation was(13.31±0.87)%,(14.33±0.97)%and(13.44±1.03)%,respectively.There were significant differences between the control group and the observation group before operation,between the observation group before operation and 6 months after operation(P<0.05).There was no significant difference between the control group and the observation group 6 months after operation(P>0.05).The preoperative RDW in children with mild,moderate and severe OSAHS was(13.28±0.67)%,(14.43±0.83)%and(14.98±0.61)%,respectively.There was significant difference among the three groups(P<0.05).Conclusion RDW significantly increases in children with OSAHS,which can be used as an assistant judgment index of the severity of OSAHS in children.