经皮冠状动脉介入术联合血栓抽吸治疗急性ST段抬高型心肌梗死的临床疗效及安全性评价

Evaluation on clinical efficacy and safety of percutaneous coronary intervention combined with thrombus aspiration in the treatment of acute ST segment elevation myocardial infarction

目的 探究经皮冠状动脉介入术联合血栓抽吸治疗急性ST段抬高型心肌梗死的临床疗效及安全性,为临床医师选择合理治疗方案提供参考。方法 82例急性ST段抬高型心肌梗死患者作为研究对象,依据随机数字表法分为对照组与试验组,每组41例。对照组给予经皮冠状动脉介入术治疗,试验组给予经皮冠状动脉介入术联合血栓抽吸治疗。比较两组患者血流和心电图结果;治疗前后左室射血分数(LVEF)水平;心血管事件发生情况。结果 治疗后,两组患者心肌梗死溶栓治疗(TIMI)血流等级3级占比、慢血流/无血流占比比较差异均无统计学意义(P>0.05);试验组患者ST段回落占比高于对照组,差异具有统计学意义(P<0.05)。治疗前,两组患者的LVEF水平比较差异无统计学意义(P>0.05);治疗后,两组患者的LVEF水平均高于治疗前,且试验组患者的LVEF水平高于对照组,差异均具有统计学意义(P<0.05)。试验组患者的心血管事件发生率0显著低于对照组的9.76%,差异具有统计学意义(P<0.05)。结论 在急性ST段抬高型心肌梗死患者治疗中,经皮冠状动脉介入术联合血栓抽吸治疗能够改善患者心功能,预防心血管事件发生,值得借鉴。

Objective To investigate the clinical efficacy and safety of percutaneous coronary intervention combined with thrombus aspiration in the treatment of acute ST segment elevation myocardial infarction,so as to provide reference for clinicians to choose a reasonable treatment regimen.Methods A total of 82 patients with acute ST segment elevation myocardial infarction as study subjects were divided intocontrol group and experimental group by random number table method,with 41 cases in each group.The control group received percutaneous coronary intervention,and the experimental group received percutaneous coronary intervention combined with thrombus aspiration.The blood flow and electrocardiogram results,left ventricular ejection fraction(LVEF)before and after treatment,occurrence of cardiovascular events was compared between the two groups.Results After treatment,there was no statistically significant difference in thrombolytic in proportion of myocardial infarction(TIMI)blood flow grade 3 and slow blood flow/no blood flow ratio between the two groups(P>0.05).The proportion of ST segment falling in the experimental group was higher than that in the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference in LVEF level between the two groups(P>0.05).After treatment,the LVEF level in the two groups was higher than those before treatment,and the LVEF level in the experimental group was higher than that in the control group.Their difference was statistically significant(P<0.05).The incidence of cardiovascular events 0 in the experimental group was significantly lower than 9.76%in the control group,and the difference was statistically significant(P<0.05).Conclusion In the treatment of patients with acute ST segment elevation myocardial infarction,percutaneous coronary intervention combined with thrombus aspiration can improve the cardiac function and prevent the occurrence of cardiovascular events.It is worthy of reference.