美多巴联合恩他卡朋治疗帕金森病的临床作用

The clinical effect of medoba combined with entacapone in the treatment of Parkinson’s disease

目的:分析美多巴联合恩他卡朋治疗帕金森病(PD)的临床疗效。方法:2017年1月-2018年12月收治PD患者80例,随机分为两组,各40例。对照组应用药物美多巴治疗;观察组应用美多巴联合恩他卡朋治疗。比较两组治疗效果。结果:观察组治疗后抑郁程度及日常活动能力评分均优于对照组,治疗总有效率高于对照组,差异有统计学意义(P<0.05)。结论:美多巴联合恩他卡朋治疗PD患者疗效显著,可有效改善患者抑郁情绪及日常活动能力。

Objective:To explore the clinical effect of medoba combined with entacapone in the treatment of Parkinson's disease(PD).Methods:From January 2017 to December 2018,80 PD patients were selected and randomly divided into two groups of 40 cases in each.The control group was treated with medoba,while the observation group was treated with medoba combined with entacapone.We compared the efficacy of the two groups.Results:In the observation group,the scores of post-treatment depression and daily activity ability were better than those in the control group,and the total effective rate was higher than that in the control group;the difference was statistically significant(P<0.05).Conclusion:The clinical effect of medoba combined with entacapone in the treatment of PD is significant.It can effectively improve the depression and the ability of daily activities.