孕早期空腹血糖筛查妊娠期糖尿病的临床价值

Clinical Value of Fasting Blood Glucose Screening for Gestational Diabetes in Early Pregnancy

目的探究孕早期空腹血糖筛查妊娠期糖尿病的临床价值。方法随机选取该院在2017年3月—2018年4月期间的孕妇86名作为研究对象,其中妊娠期糖尿病孕妇43例,正常孕妇同样也是43名,正常孕妇为对照组,妊娠期糖尿病孕妇为观察组,采集两组孕妇的孕早期空腹血糖值,对两组孕妇进行糖化血红蛋白和血红蛋白进行测定,以及分析妊娠糖尿病在在首次产检空腹血糖中的影响。结果观察组孕妇的孕早期空腹血糖平均值(5.09±0.54)mmol/L明显高于对照组(4.64±0.31)mmol/L(t=4.739,P=0.000);观察组的孕早期血红蛋白含量(128.67±10.43)g/dL也明显高于对照组(124.32±9.67)g/dL,差异有统计学意义(t=2.005,P=0.048<0.05);然而比较两组孕妇的糖化血红蛋白,观察组(5.21±0.67)%,对照组(5.09±1.13)%,差异无统计学意义(t=0.599,P=0.551)。结论孕早期空腹血糖筛查预测妊娠性糖尿病的发生有重要意义,及时应用干预,可以降低妊娠期糖尿病的反生概率,使血糖得到控制,在临床治疗中值得推广和运用。

Objective To investigate the clinical value of fasting blood glucose screening for gestational diabetes in early pregnancy.Methods A total of 86 pregnant women from March 2017 to April 2018 in our hospital were randomly selected as the study subjects,including 43 pregnant women with gestational diabetes and 43 normal pregnant women.The normal pregnant women were the control group,and the pregnant women with gestational diabetes;in the observation group,the fasting blood glucose values of the two groups of pregnant women were collected,the glycosylated hemoglobin and hemoglobin were measured in the two groups of pregnant women,and the influence of gestational diabetes on the fasting blood glucose in the first check was analyzed.Results The average fasting blood glucose of pregnant women in the observation group(5.09±0.54)mmol/L was significantly higher than that of the control group(4.64±0.31)mmol/L(t=4.7391,P=0.000).The early pregnancy was also hemoglobin(128.67±10.43)g/dL,significantly higher than the control group(124.32±9.67)g/dL,the difference was statistically significant(t=2.005,P=0.048<0.05);however,the glycosylated hemoglobin of the two groups of pregnant women was compared,the observation group(5.21±0.67)%,the control group there was no significant difference between(5.09±1.13)%(t=0.599,P=0.551).Conclusion Fasting blood glucose screening in early pregnancy predicts the occurrence of gestational diabetes.The timely application of intervention can reduce the anti-probability of gestational diabetes and control blood glucose.It is worthy of promotion and application in clinical treatment.