癫痫的脑血流动力学研究进展

Progress of Cerebral Hemodynamics in Epilepsy

癫痫不同发作阶段脑组织的局部会有不同的血流变化:发作期,癫痫灶内血流量增快、神经组织代谢率增高;间歇期,癫痫灶内血流量减慢、神经组织代谢率降低。研究癫痫不同阶段的脑血流变化特点,可能为癫痫的研究提供一条新的思路。近年来有关癫痫脑血流动力学的研究一直未被重视。本文就癫痫的脑血流动力学变化特点及可能的机制做一简要综述。

There are different changes of cerebral blood flow in different stages of epileptic seizure.During epileptic seizure,cerebral blood flow increased and brain tissue metabolic rate increased in epileptic focus;while during the intermittent period,cerebral blood flow slowed and brain tissue metabolic rate decreased.It is of great significance to study the characteristics of cerebral blood flow changes in epileptic focus in different stages of epileptic seizures,which will help to elucidate the pathogenesis of seizure.This article reviewed the progress in cerebral hemodynamics and possible mechanism of epilepsy.