肝功与血脂血清学指标水平检验在脂肪肝诊断中的应用

Application of Liver Function and Serum Lipid Levels in Diagnosis of Fatty Liver

目的研究肝功与血脂血清学指标水平检验在脂肪肝诊断中的应用。方法选取2018年1月~2019年1月在我院治疗的35例脂肪肝患者设为脂肪肝组,另选取同期在我院健康体检者35例为对照组,比较两组天冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)。结果脂肪肝组AST(81.556.82)U/L、ALT(57.23±7.85)U/L水平高于对照组(41.17±6.19)U/L、(25.88±5.86)U/L,差异有统计学意义(P<0.05);脂肪肝组TC(6.86±1.31)mmol/L、TG(2.36±1.22)mmol/L、LDL-C(3.981.31)mmol/L水平高于对照组(4.22±1.08)mmol/L、(1.23±0.65)mmol/L、(3.98±1.31)mmol/L,HDL-C(1.06±0.78)mmol/L低于对照组(1.06±0.78)mmol/L,差异有统计学意义(P<0.05)。结论脂肪肝患者肝功与血脂血清学指标水平与健康者存在差异,临床可通过筛查肝功与血脂血清学指标脂肪肝,为早期诊治提供参考依据。

Objective To study the application of liver function and serum lipid levels in the diagnosis of fatty liver.Methods 35 patients with fatty liver treated in our hospital from January 2018 to January 2019 were selected as the fatty liver group,and 35 healthy patients who underwent physical examination in our hospital during the same period were selected as the control group.Aspartate aminotransfer Enzymes(AST),alanine aminotransferase(ALT),total cholesterol(TC),triglycerides(TG),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C).Results The levels of AST(81.556.82)U/L and ALT(57.23±7.85)U/L in the fatty liver group were higher than those in the control group(41.17±6.19)U/L and(25.88±5.86)U/L,the difference was statistically significant(P<0.05);the levels of TC(6.86±1.31)mmol/L,TG(2.36±1.22)mmol/L,and LDL-C(3.981.31)mmol/L were higher in the fatty liver group than in the control group(4.22±1.08)mmo/L,(1.23±0.65)mmol/L,(3.98±1.31)mmol/L,HDL-C(1.06±0.78)mmol/L is lower than the control group(1.06±0.78)mmol/L,the difference was statistically significant(P<0.05).Conclusion The serum levels of liver function and lipids in patients with fatty liver are different from those in healthy subjects.Screening for liver function and serum lipids in patients with fatty liver can provide a reference for early diagnosis and treatment.