奥美拉唑联合立止血治疗肝硬化并上消化道出血的疗效分析

Analysis of Efficacy of Omeprazole Combined with Reptilase in the Treatment of Cirrhosis with Upper Gastrointestinal Hemorrhage

目的:探讨奥美拉唑联合立止血治疗肝硬化并上消化道出血的疗效分析。方法:选取我院收治的肝硬化并上消化道出血患者60例,随机分为对照组和治疗组,每组30例。对照组给予奥美拉唑联合酚磺乙胺治疗,治疗组给予奥美拉唑联合立止血治疗,比较2组治疗效果。结果:治疗组总有效率96.67%明显高于对照组80.00%(P<0.05);治疗组平均止血时间以及平均输血量均明显少于对照组(P<0.05);治疗组治疗后血红蛋白(Hb)水平明显高于对照组(P<0.05),治疗组治疗后尿素氮(BUN)水平明显低于对照组(P<0.05)。结论:奥美拉唑联合立止血治疗肝硬化并上消化道出血临床效果良好。

Objective: To explore the efficacy of omeprazole combined with reptilase in the treatment of cirrhosis with upper gastrointestinal hemorrhage. Methods: 60 patients with cirrhosis and upper gastrointestinal hemorrhage admitted to our hospital were selected and randomly divided into control group and treatment group, with 30 cases in each group. Control group was given omeprazole combined with etamsylate, and treatment group was given omeprazole combined with reptilase. The treatment effects were compared between the two groups. Results: The total effective rate in treatment group was significantly higher than that in control group(96.67% vs 80.00%)(P<0.05). The average hemostasis time and average blood transfusion volume in treatment group were significantly lower than those in control group(P<0.05). Hemoglobin(Hb) level in treatment group after treatment was significantly higher than that in control group(P<0.05) while the level of blood urea nitrogen(BUN) in treatment group after treatment was significantly lower than that in control group(P<0.05). Conclusions: Omeprazole combined with reptilase has good clinical effects in the treatment of cirrhosis with upper gastrointestinal hemorrhage.