磁共振弥散加权成像在胃癌诊治中的应用

Application of diffusion weighted imaging in diagnosis and therapeutic response evaluation of gastric cancer

胃癌是全球最常见的恶性肿瘤之一,治疗仍以外科手术为主,放化疗为辅。磁共振(MRI)弥散加权成像(DWI)能够检测活体组织内水分子扩散运动,通过测量表观扩散系数(ADC)值提供定量信息;体素内不相干运动弥散加权成像(IVIM-DWI)能将水的真性扩散与微循环灌注区分开来,弥补了传统DWI的不足。这些技术在胃癌的诊断与治疗反应评价中均具有重要价值。本文对DWI在胃癌的诊断、分期、病理相关性及治疗反应评估中的应用现状进行综述。

Gastric cancer is one of the most common malignant tumors in the world. Surgical resection is currently considered to be the main treatment method, supplemented by radiotherapy and chemotherapy. Diffusion-weighted magnetic resonance imaging(MRI) can detect the diffusion of water molecules in living tissues, and then provide quantitative information by measuring the apparent diffusion coefficient(ADC). Intravoxel incoherent motion diffusion weighted imaging(IVIM-DWI) can not only observe the diffusion of tissue water molecules but also reflect the blood perfusion information of tissue microcirculation. Thus, those techniques can be used to diagnose and evaluate treatment response of gastric cancer. In this article, we review the application of DWI in the diagnosis, staging, pathological correlation and therapeutic response evaluation of gastric cancer.