Caprini血栓风险评估量表在糖尿病肾病患者血栓风险中的价值研究

Studies on the Value of Caprini Thrombosis Risk Assessment Scale in the Risk of Thrombosis in Patients with Diabetic Nephropathy

目的:探讨Caprini血栓风险评估量表在糖尿病肾病患者中的应用价值。方法:随机选取我院2016年8月—2019年3月诊治的糖尿病肾病患者50例,另选取2型糖尿病患者50例为T2DM组和50例同期健康体检者为对照组,比较三组的Caprini评分和危险度分级,同时分析一般资料、血清指标与Caprini评分的关系。结果:糖尿病肾病组患者的Caprini评分为(3.66±0.99)分,明显高于T2DM组和对照组,而T2DM组又明显高于对照组(P<0.05),其中,糖尿病肾病组中的高危占42%,中危占36%。高危组患者的HbA1c和尿白蛋白定量/尿肌酐比值均明显高于中危组和低危组,组间比较差异具有统计学意义(P<0.05),但三组的空腹血糖水平比较未见统计学差异(P>0.05)。随着糖尿病肾病患者的年龄越大、体重指数越高,患者血栓形成风险越大,Caprini评分分级高危组中的年龄和体重指数均明显大于低危组和中危组(P<0.05),但糖尿病病程与Caprini评分分级未见统计学差异(P>0.05)。结论:Caprini血栓风险量表可应用于糖尿病肾病患者血栓风险的临床评估,而糖尿病肾病患者的年龄、体重指数以及尿白蛋白定量/尿肌酐比值均与血栓形成的风险有密切关系。

Objective:To investigate the application value of Caprini thrombus risk assessment scale in patients with diabetic nephropathy.Methods:50 cases of diabetic nephropathy patients diagnosed and treated in our hospital from August 2016 to March 2019 were randomly selected.Another 50 cases of type 2 diabetes patients were selected as T2DM group and 50 cases of healthy physical examination patients during the same period as the control group.Caprini scores and risk grades of the three groups were compared,and the relationship between general data,serum indicators and Caprini scores was analyzed at the same time.Results:The Caprini score of the diabetic nephropathy group was(3.66±0.99)points,which was significantly higher than that of the T2DM group and the control group,while the T2DM group was significantly higher than the control group(P<0.05).Among them,the high-risk group accounted for 42%and the medium-risk group accounted for 36%.The HbA1c and quantitative urinary albumin/urinary creatinine ratios of patients in the high-risk group were significantly higher than those in the medium-risk group and the low-risk group,with statistically significant differences between the groups(P<0.05),but no statistically significant differences were found in the comparison of fasting blood glucose levels in the three groups(P>0.05).As diabetes nephrosis patient’s age,body mass index is higher,the greater the risk of thrombosis in patients with,the greater the rating in the high-risk group Caprini age and body mass index were significantly greater than low-risk group and moderate group(P<0.05),but with the duration of diabetes Caprini rating no statistical difference(P>0.05).Conclusion:Caprini risk scale can be applied to the clinical evaluation of risk of thrombosis in patients with diabetic nephropathy,and diabetic nephropathy patient’s age,body mass index and quantitative urine albumin/uric creatinine ratio are patients there is a close relationship between the risk of thrombosis.