特发性良性阵发性位置性眩晕与骨密度的关系分析

Analysis of the relationship between idiopathic benign paroxysmal positional vertigo and bone mineral density

目的分析特发性良性阵发性位置性眩晕(BPPV)与骨密度的关系。方法选取2017年1月至2018年5月在我院神经内科就诊的49例特发性BPPV患者作为观察组,选取同期在我院体检中心体检的无头晕及眩晕病史的54例健康者作为对照组。通过双能X线吸收法检测手腕部的骨密度;比较两组骨密度分布情况、不同性别研究对象的T值、不同年龄段女性的T值。结果观察组的骨密度异常率为93.88%,显著高于对照组的74.07%(P<0.05)。观察组男性与对照组男性的T值比较,差异无统计学意义(P>0.05)。观察组女性的T值低于对照组女性(P<0.05)。两组非绝经期女性(≤49岁)的T值比较,差异无统计学意义(P>0.05)。观察组50~69、70~89岁女性的T值均低于对照组(P<0.05)。结论特发性BPPV与骨量减少、骨质疏松有明显的相关性,差异主要来源于绝经期女性。

Objective To analyze the relationship between idiopathic benign paroxysmal positional vertigo(BPPV) and bone mineral density. Methods From January 2017 to May 2018, 49 patients with idiopathic BPPV who were treated in neurology department of our hospital were selected as observation group, and 54 healthy people examined in physical examination center of our hospital who had no history of dizziness and vertigo at the same time were selected as control group. The bone mineral density of the wrist was measured by dual energy X-ray absorptiometry;the distribution of bone mineral density, T value of different gender subjects and T value of women of different ages were compared between the two groups. Results The abnormal rate of bone mineral density in the observation group was 93.88%, which was significantly higher than 74.07% in the control group(P <0.05). There was no significant difference in T value of male subject between the observation group and the control group(P>0.05). The T value of female subject in the observation group was lower than that in the control group(P<0.05). There was no significant difference in T value of non-menopausal women(≤49 years old) between the two groups(P >0.05). The T value of 50-69 and 70-89 years old women in the observation group were lower than those of the control group(P <0.05). Conclusion There is a significant correlation between idiopathic BPPV and osteopenia and osteoporosis, and the difference mainly comes from menopausal women.