腹腔镜手术联合药物辅助治疗子宫内膜异位症的临床效果

Clinical effect of laparoscopic surgery combined with drug-assisted therapy for endometriosis

目的分析腹腔镜手术联合药物辅助治疗子宫内膜异位症(EMs)的临床效果。方法选取2017年1月至2019年2月收治的108例EMs患者作为研究对象,根据不同治疗方法将其分成A组与B组,各54例。所有患者均行腹腔镜手术治疗,在此基础上A组给予米非司酮,B组给予去氧孕烯炔雌醇片。比较两组患者治疗前、后的子宫活动度、VAS评分及雌二醇水平及不良反应发生情况。结果治疗后,两组患者的子宫活动度、VAS评分及雌二醇水平均低于治疗前(P<0.05),但组间比较,差异无统计学意义(P>0.05)。治疗期间,两组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论腹腔镜手术联合米非司酮或去氧孕烯炔雌醇片治疗EMs均可改善患者子宫活动度、痛经程度及雌二醇水平。

Objective To analyze the clinical effect of laparoscopic surgery combined with drug-assisted therapy for endometriosis(EMs). Methods A total of 108 patients with EMs admitted in our hospital from January 2017 to February 2019 were selected as the study objects. The patients were divided into group A and group B according to the different treatment methods, with 54 cases in each group. All patients were given laparoscopic surgery, on this basis, the group A was treated with mifepristone, and the group B was treated with desogestrel and ethinylestradiol tablets. The uterine activity, VAS scores and estradiol levels before and after treatment and adverse reactions were compared between the two groups. Results After treatment, the uterine activity, VAS scores and estradiol levels in the two groups were lower than those before treatment(P <0.05), there were no significant differences between the two groups(P >0.05). During the treatment, there was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Laparoscopic surgery combined with mifepristone or desogestrel and ethinylestradiol tablets in the treatment of patients with EMs can improve uterine activity, dysmenorrhea and estradiol levels.