仿生表面增强拉曼散射基底的制备及其生物分析应用

Preparation of Bioinspired Surface Enhanced Raman Spectroscopy Substrate and Applications in Bioanalysis

经过数十亿年的进化和发展,自然界中的动植物体表面形成了规则的微/纳米结构和奇特功能。仿生表面增强拉曼散射(Surface enhanced Raman scattering,SERS)基底是以动植物体表面固有的规则结构或与动植物体性能相似的材料为基础而制作的基底,自发现以来,已成为SERS基底制备领域的研究热点,为解决传统SERS基底形貌和结构不均一、重现性差的问题提供了新的思路。本文介绍了仿生SERS基底及其制备方法,总结了仿生SERS基底在生物分析等方面的应用,并对其在今后的发展做了初步的展望。

After billions of years of evolution and development,the surface of animals and plants in nature has formed regular micro/nano structures and peculiar functions.Bioinspired surface enhanced Raman scattering(SERS)substrate is a kind of substrate material with the regular structure or similar property to the animals and plants.It has become a research hotpot in the field of SERS substrate since it was discoveried.And it also provides a new idea for solving the non-uniform morphology and structure of traditional SERS substrate.In this paper,we introduced the bioinspired SERS substrate and its preparation method,summarized the application of the bioinspired SERS substrate,and made a preliminary outlook for its future development.