生理盐水联合地塞米松鼻腔冲洗液在鼻窦炎鼻内镜术后患者中的应用

Application of normal saline combined with Dexamethasone Nasal Irrigation Solution in patients with sinusitis and nasal endoscopic surgery

目的探讨生理盐水联合地塞米松鼻腔冲洗液在鼻窦炎鼻内镜术后患者中的应用。方法回顾性分析2019年1~9月我院收治的120例慢性鼻窦炎患者的临床资料,按照术后鼻腔冲洗液的不同分为对照组(60例)和观察组(60例)。对照组术后采用生理盐水进行鼻腔冲洗,观察组术后采用生理盐水联合地塞米松进行鼻腔冲洗。比较两组的症状变化、鼻腔黏膜上皮化时间和鼻腔纤毛传输速度。结果治疗前,两组分泌物、黏膜充血、鼻甲肿大、鼻塞头痛评分比较,差异无统计学意义(P>0.05);治疗后,观察组分泌物、黏膜充血、鼻甲肿大、鼻塞头痛评分均低于对照组,差异有统计学意义(P<0.05);观察组鼻腔黏膜上皮化时间短于对照组,鼻腔纤毛传输速度快于对照组,差异有统计学意义(P<0.05)。结论生理盐水与地塞米松鼻腔冲洗液联合应用,慢性鼻窦炎鼻内镜术后患者的鼻部症状得到显著改善,缩短了鼻腔黏膜上皮化时间,恢复鼻腔纤毛传输速度,使患者获益。

Objective To investigate the application of normal saline combined with Dexamethasone Nasal Irrigation Solution in patients with sinusitis and nasal endoscopic surgery.Methods The clinical data of 120 patients with chronic sinusitis admitted to our hospital from January to September 2019 were retrospectively analyzed.They were divided into the control group(60 cases)and the observation group(60 cases)according to the postoperative nasal irrigation solution.The control group received nasal irrigation with normal saline after operation,and the observation group received nasal irrigation with normal saline and Dexamethasone after operation.Symptom changes,nasal mucosal epithelialization time,and nasal ciliary transmission rate were compared between the two groups.Results Before treatment,there was no significant difference in the scores of secretions,mucosal congestion,turbinate enlargement,and nasal congestion headache between the two groups(P>0.05).After treatment,secretion,mucosal congestion,turbinate enlargement,and nasal congestion headache scores of the observation group were lower than that of the control group,the differences were statistically significant(P<0.05);the nasal mucosal epithelialization time in the observation group was shorter than that in the control group,and the nasal ciliary transmission speed was faster than that of the control group,the difference was statistically significant(P<0.05).Conclusion Combined with saline and Dexamethasone Nasal Irrigating Solution,the nasal symptoms of patients with chronic sinusitis after nasal endoscopic surgery are significantly improved,which greatly shortens the time of nasal mucosal epithelialization and restores the nasal cilia transmission speed,which promotes patients′benefit.