炎症性肠病肾损害的临床病理分析

Clinicopathological analysis of renal damage in inflammatory bowel disease

目的了解炎症性肠病肾脏损害的临床及病理特点。方法对2010年5月~2018年12月在我院诊断为炎症性肠病肾损害的21例患者的临床资料进行分析、总结,对其中行肾穿刺活检的13例患者的活检病理特点进行描述。结果21例炎症性肠病肾损害患者中,男7例,女14例,溃疡性结肠炎患者16例,克罗恩病患者5例。其中13例患者行肾穿刺活检,病理类型包括IgA肾病6例,膜性肾病3例,间质性肾炎3例,新月体肾炎1例。结论IBD患者可以出现不同类型的病理损害,其中以IgA肾病、间质性肾炎以及膜性肾病最为常见。

Objective To investigate the clinical and pathological features of renal damage in inflammatory bowel disease.Methods The clinical data of 21 patients who were diagnosed with renal damage in inflammatory bowel disease in our hospital from May 2010 to December 2018 were analyzed and summarized,and the biopsy pathological characteristics of 13 of them who received needling biopsy of kidney were described.Results Among the 21 patients with renal damage in inflammatory bowel disease,7 were male,14 were female,16 were with ulcerative colitis and 5 were with Crohn’s disease.Thirteen patients were given needling biopsy of kidney,and IgA nephropathy(6 cases),membranous nephropathy(3 cases),interstitial nephritis(3 cases),and crescent nephritis(1 case)were included in the pathological types.Conclusion IBD patients can have different types of pathological damage,of which IgA nephropathy,interstitial nephritis and membranous nephropathy are the most common.