安痛方坐浴治疗功能性肛门直肠痛的疗效观察

Observation on the therapeutic effect of sitz bath with Antong recipe in the treatment of functional anorectal pain

目的观察安痛方坐浴治疗功能性肛门直肠痛(FAP)患者的临床疗效。方法将71例FAP患者按随机数字表法分为2组。对照组36例(后退出1例)采用温水坐浴加吲哚美辛栓纳肛治疗;治疗组35例采用安痛方坐浴治疗。2组疗程为14 d。比较2组治疗前后疼痛视觉模拟评分(VAS)及健康调查简表(SF-36)评分的变化情况。结果治疗组总有效率82.86%,对照组总有效率71.43%,治疗组疗效优于对照组(P<0.05)。治疗后2组疼痛VAS均降低(P<0.05),治疗组治疗后疼痛VAS低于对照组(P<0.05)。治疗后2组SF-36各项评分中除一般健康(GH)和情感职能(RE)无明显变化外,其余各项评分均升高(P<0.05),且治疗组改善均优于对照组(P<0.05)。结论安痛方坐浴治疗FAP的临床疗效确切,具有安全性良好、不良反应少等优势。

Objective To observe the effect of sitz bath with Antong recipe in the treatment of functional anorectal pain(FAP). Methods 71 FAP patients were divided into two groups according to the random number table method. 36 cases in control group(1 case withdrew afterwards) were treated by warm water sitz bath and indomethacin suppository for anus. 35 cases in treatment group were treated by sitz bath with Antong recipe. The course of treatment was 14 days. The changes of visual analogue pain scale(VAS) and health survey summary(SF-36) were compared before and after treatment. Results The total effective rate was 82.86% in treatment group and 71.43% in control group. The clinical curative effect of the treatment group was better than that of the control group(P<0.05). After treatment, VAS of pain in both groups was decreased(P<0.05), and the treatment group was lower than the control group(P<0.05). After treatment, SF-36 scores of the two groups were increased(P<0.05), except for general health(GH) and emotional function(RE), and the improvement of the treatment group was better than that of the control group(P<0.05). Conclusion the therapeutic effect of Antang formula on FAP is definite, which has the advantages of good safety and less adverse reactions.