基于数据挖掘分析沈舒文教授治疗泄泻组方规律

Analysis of professor Shen Shuwen′ s prescription for diarrhea based on data mining

目的运用数据挖掘分析沈舒文教授治疗泄泻组方规律。方法收集2016年1月~2018年12月于陕西中医药大学附属医院名医工作室及陕西中医药大学第二附属医院名医馆被诊断为“泄泻”患者的处方,借助中医传承辅助系统,运用关联规则、复杂系统熵聚类等方法从用药频次、组方规律、核心药对及潜在新方等方面进行分析。结果共纳入处方192首,涉及中药170味,核心药对8组,4首潜在新方。结论从数据分析结果可知沈舒文教授治疗泄泻用药以炒白术、陈皮、白芍、补骨脂、肉豆蔻等最多,以温、平性药物为主,五味以辛、苦、甘为著;故治疗将健脾益气放在首位。

Objective To analyze the rules of professor Shen Shuwen′s prescriptions for diarrhea by using data mining.Methods The prescriptions of the patients diagnosed as“diarrhea”in the Famous Medical Studio of Affiliated Hospital of Shaanxi University of Chinese Medicine and the Famous Medical Center of the Second Affiliated Hospital of Shaanxi University of Chinese Medicine from January 2016 to December 2018 were collected.With the aid of the auxiliary system of traditional Chinese medicine inheritance,the methods such as association rules,entropy clustering of complex systems were used to analyze the frequency of drug use,the rules of formula formation,core drug pairs and potential new prescriptions.Results One hundred and ninety-two prescriptions were included,involving 170 flavors of traditional Chinese medicine,and 8 groups of core drugs and 4 potential new prescriptions were used.Conclusion According to the results of data analysis,professor Shen Shuwen used properties of drugs for diarrhea are mainly based on warm and mild drugs,such as Fried Rhizoma Atractylodis Macrocephalae,Pericarpium Citri Reticulatae,Radix Paeoniae Alba,Fructus Psoraleae,Semen Myristicae,etc.In addition to pungent,bitter and sweet drugs are main flavours of the five flavours.Therefore,Jianpi Yiqi is put in the first in the treatment of diarrhea.