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螺内酯与血管紧张素转换酶抑制剂(ACEI)联合冻干重组人脑利钠肽治疗难治性心力衰竭患者的临床研究 被引量:2

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摘要 目的研究分析对难治性心力衰竭患者开展螺内酯与血管紧张素转换酶抑制剂(ACEI)联合冻干重组人脑利钠肽治疗临床效果。方法纳入我院2016年9月至2018年11月期间收治的难治性心力衰竭患者200例为研究对象,根据患者住院编号分为研究组(100例)及参照组(100例),参照组患者开展难治性心力衰竭的常规治疗,研究组患者在此基础上联合给予螺内酯与血管紧张素转换酶抑制剂(ACEI)联合冻干重组人脑利钠肽治疗,对两组患者临床治疗效果、治疗前后LVEF、LVEDD、CO等心功能指标改善情况进行评定比较。结果治疗12周后研究组患者临床治疗总有效率显著高于参照组(P<0.05);同时两组患者LVEF、LVEDD、CO等指标均有显著改善(P<0.05),而研究组患者各指标改善情况均显著优于参照组(P<0.05)。结论相较于常规治疗,螺内酯与血管紧张素转换酶抑制剂(ACEI)联合冻干重组人脑利钠肽治疗难治性心力衰竭能够显著改善患者心功能,提升临床治疗的效果,值得推广。
机构地区 联勤保障部队第
出处 《心血管病防治知识(学术版)》 2019年第21期33-35,共3页 Prevention and Treatment of Cardiovascular Disease
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