慢性髓系白血病慢性期患者健康相关生活质量调查

Survey on health-related quality of life in patients with chronic phase of chronic myeloid leukemia

目的评估使用酪氨酸激酶抑制剂(TKI)的慢性髓系白血病(CML)慢性期患者的健康相关生活质量(HRQOL)。方法分析2017年11月至2018年8月在西部战区空军医院及四川省人民医院门诊接受TKI治疗的112例CML患者HRQOL的影响因素。结果女性、农村户籍、年龄大于或等于45岁、伴随疾病大于或等于2种、年医疗费用大于或等于4万、TKI使用时间大于或等于5年、现阶段疗效更差患者的HRQOL更差。结论降低年医疗费用及提高疗效可改善患者HRQOL,评估CML患者的伴随疾病对确定需要改善HRQOL的患者非常重要。

Objective To assess the health-related quality of life(HRQOL)in the patients with chronic myeloid leukemia in chronic phase(CML-CP)using the tyrosine kinase inhibitor(TKI).Methods The influencing factors of HRQOL in 122 cases of CML receiving TKI treatment in the Air Force Hospital of Western War Zone and Sichuan Provincal People′s Hospital from November 2017 to August 2018 were analyzed.Results Female,rural household registration,age≥45 years old,accompanying diseases≥2 kinds,annual medical expenses≥40000 Yuan,KTI use time≥5 years and the patients with poorer treatment effect at the present stage had worse HRQOL.Conclusion Reducing the annual medical costs and improving treatment effects can improve the patient′s HRQOL,and assessing concomitant diseases in CML patients is very important for identifying the patients needing to improve HRQOL.