血管新生在心肌梗死中作用机制的研究进展

Research Advancement of Mechanism of Angiogenesis in Myocardial Infarction

血管新生是指从已有的毛细血管或毛细血管后静脉发展而形成新的血管,是一个涉及多种细胞的多种分子的复杂过程。血管新生除对于恶性实体肿瘤外,在心血管疾病特别是缺血性心脏病中具有极其重要的意义。本文对血管新生机制进行了简单介绍,尤其是对与血管新生密切相关的多种调节因子、炎症因子以及凋亡相关因子等进行了初步探讨。

Angiogenesis refers to the formation of new blood vessels from existing capillaries or retro-capillary veins.It is a complex process involving manymolecules of various cells.In addition to malignant solid tumors,angiogenesis plays an important role in cardiovascular diseases,especially ischemic heart dsease.In this paper,the mechanism of angiogenesis is briefly introduced,especially the various regulatory factors,inflammatory factors and apoptotic related factors closely related to angiogenesis are preliminarily discussed.