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OGF-OGFr通路与肿瘤治疗研究进展

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摘要 传统上,针对内源性和外源性阿片类肽及其受体的研究都集中在疼痛的介导及超量应用导致成瘾上。阿片生长因子(OGF)是一种自分泌产生的内源性阿片类肽,它能与OGF受体(OGFr)相结合,下调细胞周期蛋白依赖性抑制性激酶,抑制DNA合成,使细胞周期阻滞于G(1)/S期。
出处 《中国老年学杂志》 CAS 北大核心 2020年第3期668-672,共5页 Chinese Journal of Gerontology
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