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抗内皮细胞抗体检测临床应用研究进展 被引量:2

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摘要 抗内皮细胞抗体(AECA)是一类针对内皮细胞结构组成的一种复杂抗体,其以血管内皮细胞(EC)表面或吸附于EC表皮的一组异质性抗原为作用靶标,通过形成免疫复合物发挥破坏内皮细胞的作用,从而导致血管损伤,使患者产生与之相关的一系列临床症状。较多研究表明,AECA不仅广泛参与了临床疾病的发病机制,还与疾病病情活动呈正相关。AECA可能作为一种有价值的血清学指标,用于对临床疾病的诊断、治疗及预后。近年来有关AECA与临床部分疾病相关性的研究不断涌现,本文就相关研究予以综述。
出处 《现代医药卫生》 2020年第3期374-376,共3页 Journal of Modern Medicine & Health
基金 国家自然科学基金项目(81560012) 贵州省科技计划项目(黔科合基础〔2017〕1100、黔科合〔2016〕支撑2907)
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