摘要
目的:探讨复方紫草油并普朗特凝胶伤口敷料治疗慢性创面临床疗效。方法:选取2017年9月至2019年9月南京市中西医结合医院收治的确诊慢性创面患者90例作为研究对象,按照随机数字表法分为观察组(n=32),对照A组(n=30),对照B组(n=28)。其中观察组采用复方紫草油并普朗特凝胶伤口敷料治疗局部创面,对照A组采用普朗特凝胶伤口敷料治疗局部创面,对照B组采用复方紫草油治疗局部创面。对比观察3组临床疗效、创面愈合状况、创面愈合时间及创面细菌阳性率等因素。结果:治疗后,1)观察组总有效率为93.75%,对照A组总有效率73.33%,对照B组总有效率67.86%,观察组与对照组分别比较,差异有统计学意义(P<0.05);2)创面愈合率对照观察组明显优于对照A组和对照B组,差异有统计学意义(P<0.05);3)局部症状体征积分、全身症状体征、总积分比较观察组均优于对照A组对照B组,差异有统计学意义(P<0.05);4)观察组创面细菌阳性率明显低于对照A组和对照B组,差异有统计学意义(P<0.05);结论:复方紫草油并普朗特凝胶伤口敷料治疗下肢慢性溃疡临床疗效显著,有推广价值。
Objective:To investigate the clinical efficacy of Compound Zicao Oil and Prande gel wound dressing in the treatment of chronic wounds.Methods:A total of 90 patients with chronic wounds in Nanjing Hospital of Integrated Traditional Chinese and Western Medicine from September 2017 to September 2019 were selected and randomly divided into 3 groups according to the random number table:a treatment group and a control group A and a control group B.The treatment group was treated with Compound Zicao Oil and Prande gel wound dressing to treat local wounds.In the control group A,Prande gel wound dressing was used to treat local wounds,and in the control group B,Compound Zicao Oil was used to treat local wounds.The clinical efficacy,wound healing status,wound healing time and wound bacterial positive rate of the 3 groups were compared.Results:1)After treatment the total effective rate of the treatment group was 93.75%,the total effective rate of the control group A was 73.33%,and the total effective rate of the control group B was 67.86%.The difference between the treatment group and the control group was statistically significant(P<0.05).2)Wound healing rate was significantly better in the control group than in the control group A and the control group B.The difference was statistically significant(P<0.05).3)The local symptoms and signs scores,systemic symptoms and signs,total scores were better in the treatment group than in the control group A and the control group B.The difference was statistically significant(P<0.05).4)The positive rate of bacterial infection in the treatment group was significantly lower than that in the control group A and the control group B.The difference was statistically significant(P<0.05).Conclusion:Compound Zicao Oil and Prande gel wound dressing for the treatment of chronic ulcers of lower extremity has a significant clinical effect and has a promotion value.
作者
赵有利
肖飞
裴学军
赵浩然
Zhao Youli;Xiao Fei;Pei Xuejun;Zhao Haoran(Department of Vascular and Lymphatic Surgery,Nanjing Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Nanjing University of Chinese Medicine,Nanjing 210014,China;Academy of Drug Research,Jianmin Pharmaceutical Group Co.,Ltd.,Wuhan 430052,China;Nanjing University of Chinese Medicine,Nanjing 210046,China)
出处
《世界中医药》
CAS
2019年第12期3298-3301,共4页
World Chinese Medicine
基金
中国人口福利基金会妇幼关爱基金-科研支撑计划(FY201711350894)
南京市卫计委第15批科技发展项目(201715055)
关键词
复方紫草油
伤口敷料
慢性创面
对比研究
Compound Zicao Oil
Wound dressing
Chronic wound surface
Comparative study