儿童血清肺炎支原体抗体检测及意义

Detection and Significance of Serum Mycoplasma Pneumoniae Antibody in Children

目的探讨儿童血清肺炎支原体抗体检测的临床意义。方法选取2018年5月至2019年5月在内蒙古自治区赤峰市克什克腾旗人民医院进行就诊并且接受肺炎支原体抗体检测的300例患儿作为对象,将患儿根据年龄阶段分为0~5岁100例,6~10岁100例,11~14岁100例,观察各组的支原体抗体的阳性检出情况。采用ELISA间接法、间接免疫荧光法对血清肺炎支原体抗体进行检测。结果各年龄阶段组患儿肺炎支原体抗体阳性检出概率比较,数据差异有统计意义(P<0.05)。其中,0~5岁阳性率是20%;6~10岁阳性率是41%,11~14岁阳性率是49%。不同性别患儿的血清肺炎支原体抗体检测结果比较,数据差异无统计意义(P>0.05)。结论儿童血清肺炎支原体抗体检测具有重要的临床价值。

Objective To investigate the clinical significance of detection of serum Mycoplasma pneumoniae antibody in children.Methods From May 2018 to May 2019,300 children from the People's Hospital of Keshiketengqi,Chifeng City,Inner Mongolia Autonomous Region were enrolled and tested for antibodies against Mycoplasma pneumoniae.The children were divided into 0 to 5 according to age.There were 100 patients in the age group,100 patients in the 6~10 age group,and 100 patients in the 11~14 age group.The positive detection of mycoplasma antibodies in each group was observed.Serum Mycoplasma pneumoniae antibodies were detected by ELISA indirect method and indirect immunofluorescence assay.Results The positive detection rate of Mycoplasma pneumoniae antibody in children of different age groups was statistically significant(P<0.05).Among them,the positive rate of 0~5 is 20%;the positive rate of 6~10 years old is 41%,and the positive rate of 11~14 years old is 49%.There was no statistical difference in the data of serum Mycoplasma pneumoniae antibody between children of different genders(P>0.05).Conclusion The detection of serum Mycoplasma pneumoniae antibody in children has important clinical value.