血清和肽素对急性心肌梗死的早期诊断价值

Early Diagnostic Value of Serum Copeptin in Acute Myocardial Infarction

目的探究血清和肽素对急性心肌梗死的早期诊断价值。方法对2016年4月至2017年8月黑龙江省医院南岗分院收治的84例疑似急性心肌梗死患者进行病情回顾分析。将患者平均分为观察组与对照组,各42例,观察组行和肽素联合肌钙蛋白I水平检测,对照组行肌钙蛋白I水平检测。对比两组诊断价值。结果发病时间4 h内,观察组较对照组诊断灵敏度显著增加,特异性显著下降(P<0.05)。肌钙蛋白I水平在患者胸痛发作6 h后升高,24 h为最大值。和肽素在患者胸痛发作4 h内升高,6 h后逐渐下降。结论和肽素联合肌钙蛋白I检测对发病4 h内急性心肌梗死患者病情的诊断具有良好的灵敏度。

Objective To explore the early diagnostic value of serum copeptin in acute myocardial infarction.Methods A total of patients with suspected acute myocardial infarction admitted to Nangang Branch of Heilongjiang Hospital from April 2016 to August 2017 were retrospectively analyzed.The patients were divided into the observation group and control group,42 cases in each group.The copeptin and troponin I levels of the observation group were detected,while the troponin I level of the control group was detected.The specificity and sensitivity of the two groups were compared.Results Within 4 h of onset,the diagnostic sensitivity of the observation group was higher than the control group,and the diagnostic specificity of the observation group was lower than the control group(P<0.05).Troponin I levels increased 6 h after the onset of chest pain,with a maximum of 24 h.And copeptin increased within 4 h after the onset of chest pain,and decreased gradually after 6 h.Conclusion The detection of troponin I combined with copeptin has a good sensitivity in the diagnosis of patients with acute myocardial infarction within 4 h of onset.