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不同程度病情类风湿关节炎患者血清IL-32、GM-CSF、COMP水平变化及临床意义 被引量:1

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摘要 目的探讨不同程度病情类风湿关节炎(rheumatoid arthritis,RA)患者血清白细胞介素-32(IL-32)、粒细胞巨噬细胞集落刺激因子(GM-CSF)、软骨寡聚基质蛋白(COMP)水平变化及临床意义。方法选取2017年3月~2019年4月我院RA患者63例作为观察组,另选同期健康体检者40例作为对照组。均检测血清IL-32、GM-CSF、COMP水平,对比两组上述指标水平变化,分析血清IL-32、GM-CSF、COMP水平与RA病情程度关联性。结果观察组血清IL-32、GM-CSF、COMP水平高于对照组(P<0.05);活动期患者血清IL-32、GM-CSF、COMP水平高于缓解期(P<0.05);经Spearman分析,RA病情程度与血清IL-32、GM-CSF、COMP水平呈正相关(P<0.05),结论血清IL-32、GM-CSF、COMP水平变化与RA发病、发展关系密切,检测上述指标对早期确诊RA,监测病情变化具有重要作用。
作者 唐尧宇
出处 《医学新知》 CAS 2019年第6期648-649,共2页 New Medicine
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