响应面法优化乳化型热不可逆复合凝胶配方

Optimization of Emulsified Thermoreversible Composite Gel Formula by Response Surface Methodology

以钙化海藻酸钠、亚麻籽胶、结冷胶、酪蛋白酸钠、大豆油为原料,通过单因素实验和Box-Behnken响应面法,优化一种热不可逆复合凝胶配方。以复合凝胶的硬度和弹性为响应值,按5种原料的不同添加量进行单因素实验并响应面优化。结果表明,热不可逆复合凝胶的最优配方为:钙化海藻酸钠浓度5%、亚麻籽胶浓度1.11%,结冷胶浓度1.12%,酪蛋白酸钠浓度1.32%,大豆油浓度15%。此条件下复合凝胶的硬度值为(1323.25±40.098)g,弹性值为(0.856±0.019)g,与预测值的误差均小于5%,说明该响应面模型准确度较高,所优化出的凝胶配方组合具有实际应用的意义。

A refractory composite gel formulation was optimized by single factor experiments and Box-Behnken response surface method using calcified sodium alginate,linseed gum,gellan gum,sodium caseinate and soybean oil as raw materials.Based on the hardness and elasticity of the composite gel,the single factor experiments and response surface optimization were carried out according to the different addition amounts of the five raw materials.The results showed that the optimal formulation of the thermoreversible composite gel was:5%calcified sodium alginate,1.11%linseed gum,1.12%gellan gum concentration,1.32%sodium caseinate,and 15%soybean oil.Under these conditions,the hardness of the composite gel was(1323.25±40.098)g,the elastic value was(0.856±0.019)g,and the error with the predicted value was less than 5%,which indicated that the response surface model had higher accuracy and the optimized gel formula combination had practical application significance.