BAL治疗对改善支气管扩张患者症状的作用

BAL Can Improve the Symptoms of Bronchiectasis Patients

目的探讨支气管镜肺泡灌洗(BAL)治疗支气管扩张(BE)对患者症状及微生物感染的影响。方法研究对象选择2017年1月-2017年12月期间在黄石市中心医院接受治疗的80例支气管扩张患者,将其按照数字随机表法划分为观察组和常规组,每组40例。常规组接受常规治疗,实验组同时接受支气管镜下BAL治疗,观察两组治疗效果。结果实验组治疗总有效率高于常规组(P<0.05)。实验组咳嗽咳痰、发热、肺部湿啰音缓解时间均短于常规组(P<0.05)。治疗前两组肺炎克雷伯菌、铜绿假单胞菌、大肠埃希菌、鲍氏不动杆菌、白色念珠菌、金黄色葡萄球菌感染率对比差异无统计学意义(P>0.05)。实验组患者除克雷伯菌和金黄色葡萄球菌感染数均低于常规组(P<0.05)。结论针对支气管扩张患者应用支气管镜下BAL治疗,能够减少微生物感染。

Objective To investigate the effect of bronchoscopic alveolar lavage(BAL)on bronchodilation(BE)on patients’symptoms and microbial infection.Methods The study subjects selected 80 patients with bronchiectasis who were treated in Huangshi Central Hospital from January 2017 to December 2017.They were divided into observation group and routine group according to the digital random table method,with 40 cases in each group.The conventional group received conventional treatment,and the experimental group received BAL under bronchoscope at the same time,and the treatment effect of the two groups was observed.Results The total effective rate of treatment in the experimental group was higher than that in the conventional group(P<0.05).The remission time of cough,sputum,fever and wet rales in the experimental group was shorter than that in the conventional group(P<0.05).There was no significant difference in the infection rates of Klebsiella pneumoniae,Pseudomonas aeruginosa,Escherichia coli,Acinetobacter albicans,Candida albicans,and Staphylococcus aureus in the two groups before treatment(P>0.05).The number of Klebsiella and Staphylococcus aureus infections in the experimental group were lower than those in the conventional group.Conclusion Bronchoscopic BAL treatment can reduce microbial infection in patients with bronchiectasis.