中西药物防治冠心病PCI术后支架内再狭窄

Chinese and Western Medicine for Prevention and Treatment of In-stent Restenosis After PCI

目的探讨冠心通络胶囊与双联抗血小板药物在冠心病PCI术后支架内再狭窄防治中的应用效果。方法选择2018年1月-2018年8月我院PCI术治疗的冠心病患者90例,随机双盲法划分为研究组与对照组,各45例;对照组接受常规疗法与双联抗血小板药物疗法;研究组在对照组基础上接受冠心通络胶囊给药,对比两组治疗后的心电图疗效、中医证候疗效及术后再狭窄发生率。结果研究组心电图疗效有效率为88.89%,中医证候疗效有效率为84.44%,差异有统计学意义(P<0.05);研究组的术后再狭窄发生率为4.44%,低于对照组的17.78%,组间差异有统计学意义(P<0.05)。结论接受PCI术治疗的冠心病患者被施以双联抗血小板药物、冠心通络胶囊联合给药疗法,可以改善患者心电图疗效,降低出现术后再狭窄发生率,有利于患者获取更好的预后质量。

Objective To investigate the effect of Guanxintongluo Capsule and double antiplatelet drugs in the prevention and treatment of in-stent restenosis after PCI for coronary heart disease.Methods Ninety patients with coronary heart disease who underwent PCI in our hospital from January 2018 to August 2018 were enrolled.The patients were randomly divided into study group and control group,45 cases in each group.The control group received conventional therapy and double antiplatelet.Drug therapy;the study group received Guanxin Tongluo Capsule on the basis of the control group,and compared the electrocardiogram efficacy,TCM syndrome efficacy and postoperative restenosis rate after treatment.Results The effective rate of electrocardiogram in the study group was 88.89%,and the effective rate of TCM syndrome was 84.44%.The difference between the two groups was statistically significant(P<0.05).The postoperative restenosis occurred in the study group.The rate was 4.44%,which was lower than 17.78%in the control group.The difference between the groups was statistically significant(P<0.05).Conclusion Patients with coronary heart disease undergoing PCI are treated with dual antiplatelet drugs and Guanxintongluo capsules,which can improve the electrocardiogram and reduce the incidence of postoperative restenosis,which is beneficial to patients.