冠心病心绞痛患者行丹参多酚酸盐治疗的效果

The Effect of Salvianolate on Angina Pectoris Patients With Coronary Heart Diease

目的分析冠心病心绞痛患者采取丹参多酚酸盐治疗效果及安全影响。方法选取本院2017年7月-2018年6月接收的冠心病心绞痛患者72例为研究对象,随机分为两组,各36例,对照组行丹参注射液治疗方案,研究组则接受丹参多酚酸盐治疗方案,对比两组临床疗效及不良反应发生率。结果在治疗总有效率方面,对照组是72.22%,研究组是94.44%,研究组较对照组更高,差异有统计学意义(P<0.05);在不良反应发生率方面,对照组与研究组分别是8.33%和5.56%,研究组与对照组差异统计学无意义(P>0.05);研究组心绞痛发作次数较对照组更低,差异存在统计学意义(P<0.05);而运动诱发ST段压低1 mm时间、运动诱发心绞痛发作时间及总运动代谢量,对照组与研究组差异统计学无意义(P>0.05)。结论冠心病心绞痛疾病治疗期间,应用丹参多酚酸盐治疗方案,不仅可以减少冠心病心绞痛发作次数,同时有助于改善患者临床症状,促进治疗效果的提高,此外,具有较高的安全性。

Objective To analyze the efficacy and safety of salvianolate in the treatment of coronary heart disease and angina pectoris.Methods 72 patients with angina pectoris of coronary heart disease received in our hospital from July 2017 to June 2018 were randomly divided into two groups,36 cases in each group.The control group was treated with Salvia miltiorrhiza injection,while the research group was treated with salvianolate.The clinical efficacy and the incidence of adverse reactions were compared between the two groups.Results The total effective rate of treatment was 72.22%in the control group and 94.44%in the study group.The incidence of adverse reactions in the study group was higher than that in the control group(P<0.05).The incidence of adverse reactions in the control group and the study group was 8.33%and 5.56%,respectively.The difference between the study group and the control group was statistically insignificant(P>0.05).The incidence of angina attacks in the study group was lower(P<0.05),but there was no significant difference between the control group and the control group(P>0.05)in the time of exerciseinduced ST segment depression 1 mm,the time of exercise-induced angina pectoris attack and total exercise metabolism.Conclusion Salvia miltiorrhiza polyphenolic salts can not only reduce the number of attacks of angina pectoris,but also help to improve the clinical symptoms of patients and promote the improvement of treatment effect.In addition,it has high safety and is worthy of continuous application and promotion in clinical practice.