倒班工作睡眠障碍患者的注意网络功能研究

Study on attention networks in patients with shift work sleep disorder

目的评估倒班工作睡眠障碍患者注意网络受损情况。方法对30例倒班工作睡眠障碍患者和26例规律睡眠健康对照进行注意网络测试。结果与规律睡眠健康受试者相比,倒班工作睡眠障碍患者在警觉网络效率(P<0.01)和执行控制网络效率方面明显下降(P<0.01),定向网络效率、平均反应时间和平均正确率与正常对照组相比则差异无统计学意义(P>0.05);执行控制网络效率与匹兹堡睡眠质量指数总分成正比(r=0.58,P=0.001)。结论倒班工作睡眠障碍患者警觉网络和执行网络受损,定向网络保留。

Objective To study the impairment of attention networks in patients with shift work sleep disorder(SWSD).Methods A total of 30 patients with SWSD and 26 matched healthy subjects were recruited to undergo attention network test(ANT).Results Compared with healthy subjects,the patients with SWSD showed significantly poorer efficiency on alerting attention and executive attention(P<0.01).Furthermore,efficiency on executive attention was positively associated with the scores of Pittsburgh sleep quality index(PSQI).Conclusion Our findings suggest that patients with SWSD exhibited selective impairments of attention network of alerting and executive control.