腹针治疗非典型抗精神病药物所致肥胖的治疗效果观察

Clinical observation of abdominal acupuncture in the treatment of obesity caused by atypical antipsychotics

目的探讨腹针对非典型抗精神病药物所致肥胖患者体质量、腰围、体质量指数(body mass index,BMI)及血脂的影响。方法将60例服用非典型抗精神病药物所致肥胖的患者,根据年龄、性别、病程、既往肥胖时间,按组间均衡的原则分为治疗组和对照组,每组30例。治疗组采用腹针治疗,对照组为健康指导。观察两组患者在治疗前、治疗第28天和治疗第56天体质量、腰围、BMI及血脂浓度的变化。结果对研究结果采用重复多因素方差分析,治疗组腰围、BMI、三酰甘油与对照组相比,差异有统计学意义(P<0.05),治疗组效果优于对照组。进行两两比较分析结果发现,在治疗第28天时,治疗组腰围及BMI与对照组相比,差异有统计学意义(P<0.05);第56天时,治疗组体质量、腰围、BMI、三酰甘油与对照组相比,差异有统计学意义(P<0.05),治疗组效果优于对照组。结论腹针能有效地降低服用抗精神病药物所致肥胖患者体质量、腰围、BMI,促进脂代谢,降低血脂水平。

Objective To investigate the effects of abdominal acupuncture on body weight,waist circumference,body mass index(BMI),and blood lipids in obese patients with atypical antipsychotics.Methods Sixty patients with obesity caused by atypical antipsychotics were divided into a treatment group(30 cases)and a control group(30 cases).The treatment group was treated with abdominal acupuncture,while the control group with health guidance.The changes of body weight,waist circumference,BMI and blood lipid levels of patients in the two groups before treatment were observed,on the 28th day and on the 56th day.Results Repeated multivariate analysis of variance was used to study the results.The results showed that the time effects and grouping effects on weight,waist circumference,BMI,cholesterol and triglycerides were significantly interactive(P<0.05).Further analysis indicated that the waist circumference and BMI data on the 28th day of treatment were better than the control group(P<0.05).On the 56th day,the weight,waist circumference,BMI,and triglyceride data of the treatment group were better than the control group(P<0.05),with the statistically significant difference.Conclusion Abdominal acupuncture can decrease the body weight,BMI,and lipid metabolism of obese patients with antipsychotics.