尿液中膀胱肿瘤标志物研究进展

Bladder tumor markers in urine

目前膀胱癌的早期诊断和随访监测主要依靠膀胱镜检和尿细胞学检查,两者尚有局限性。人们需要一种高敏感性、简单快捷且无创的检查方法用于膀胱癌的诊断和随访。越来越多的学者开始关注尿液中的膀胱肿瘤标记物并对其进行研究,虽然这些肿瘤标志物因为各种原因尚不足以取代膀胱镜检查,但其前景还是值得期待的。本文就目前膀胱肿瘤标记物的研究情况作一综述。

At present,the early diagnosis and follow-up monitoring of bladder cancer mainly rely on cystoscopy and urinary cytology,both of which have limitations.A highly sensitive,simple,and noninvasive method is needed for the diagnosis and follow-up of bladder cancer.More and more people begin to pay attention to and study bladder tumor markers in urine.Although these tumor markers are not enough to replace cystoscopy for various reasons,their prospects are still worth looking forward to.This article reviews the current research on bladder tumor markers.