高压氧联合药物治疗突发性耳聋的疗效分析

The clinical analysis of hyperbaric oxygen combined with drug treatment for sudden deafness

目的对比分析药物治疗及药物治疗联合高压氧治疗突发性耳聋的临床疗效。方法回顾性分析2017年1月至2018年12月本院收治的155例突发性耳聋患者作为研究对象,分为药物治疗组(对照组)及药物治疗联合高压氧治疗组(观察组),比较两组疗效。结果观察组治疗总有效率显著高于对照组(70.83%比59.04%),差异有统计学意义(P<0.05)。两组患者治疗后纯音听阈值均显著低于治疗前(均P<0.001),且观察组显著低于对照组(P<0.05)。观察组耳鸣、耳闷、头晕改善率均显著高于对照组,差异有统计学意义(P<0.05)。两组听力损伤程度与疗效的比较结果表明听力损伤度与临床有效率有关,听力损失程度越轻临床有效率越高。两组发病年龄、性别分别与疗效的比较结果均示与临床疗效无明显关系(P>0.05)。观察组不同氧疗次数与疗效的关系比较结果显示:治疗次数>10次组总有效率高于治疗次数<10次组(76.92%比63.64%),但差异无统计学意义(P>0.05)。结论药物治疗联合高压氧治疗可以提高治疗突聋的疗效,明显降低纯音听阈值,提高听力水平。

Objective To compare and analyze the clinical efficacy of drug therapy and drug therapy combined with hyperbaric oxygen for sudden deafness.Methods 155 cases of sudden deafness in our hospital from January 2017 to December 2018 were retrospectively analyzed.They were divided into drug treatment group(control group)and drug treatment combined with hyperbaric oxygen treatment group(observation group).The clinical efficacy of the two groups was observed.Results The total effective rate of treatment in the observation group was 70.83%,which was significantly higher than that in the control group(59.04%),and the difference was statistically significant(P<0.05).After treatment,the pure tone hearing thresholds of the two groups were significantly lower than those before treatment(P<0.001),and that of the observation group was significantly lower than that of the control group(P<0.05).The improvement rate of tinnitus,ear nausea,and dizziness in the observation group were significantly higher than those in the control group,and the differences were statistically significant(P<0.05).The comparison between the degree of hearing impairment and the efficacy of the two groups showed that the degree of hearing impairment was related to the clinical effective rate,the lighter the degree of hearing loss was,the higher the clinical efficiency was.The comparison of age,gender,and efficacy between the two groups showed no significant relationship with clinical efficacy(P>0.05).The relationship between the number of different oxygen treatments and the curative effect in the observation group showed that the total effective rate of patients with oxygen treatment>10 times was 76.92%,higher than that of oxygen treatment<10 times(63.64%),the difference was not statistically significant(P>0.05).Conclusion Drug therapy combined with hyperbaric oxygen therapy can improve the therapeutic effect of sudden deafness,significantly reduce the pure tone hearing thresholds,and improve the hearing level.