ICP-MS同时测定化风丹中5种常见金属元素的含量

Simultaneous Determination of the Content of Five Common Metal Elements in Huafeng Dan by ICP-MS

目的建立同时测定化风丹中铜(63Cu)、砷(75As)、镉(114Cd)、汞(202Hg)和铅(208Pb)5种常见金属元素含量的方法。方法样品用浓硝酸-双氧水(5︰1)微波消解后采用微波消解-电感耦合等离子体质谱(ICP-MS)测定5种金属元素的含量,以锗(72Ge)、铟(115In)、铋(209Bi)混合溶液作为内标。结果该方法对5种金属元素的标准曲线相关系数r>0.9992,检出限在0.001~0.055 ng·mL^-1,加样回收率在85.67%~114.14%,RSD在1.12%~4.26%。结论该方法专属性强、快速灵敏,适用于化风丹中5种常见金属元素含量的测定。

OBJECTIVE To establish a method for simultaneous determination of the content of 5 metal elements(63Cu,75As,114Cd,202Hg,208Pb)in Huafeng Dan.METHODS The samples were digested with concentrated nitric acid-hydrogen peroxide(5︰1),and then microwave digestion-inductively coupled plasma mass spectrometry(ICP-MS)was used to determine the mass concentration of 5 metal elements.72 Ge,115 In,209 Bi were used as internal standards.RESULTS The correlation coefficient of the standard curves of 5 elements was>0.9992,detection limits were in the range of 0.001-0.055 ng·mL^-1,recoveries were in the range of 85.67%-114.14%and RSDs were in the range of 1.12%-4.26%.CONCLUSION The method is specific,accurate and sensitive,and suitable for the content determination of 5 common metal elements in Huafeng Dan.