冬病夏治三伏贴联合吸入糖皮质激素治疗儿童哮喘的疗效分析

Analysis on efficacy of Sanfu Stick for treating minter disease in summer combined with inhaled glucocorticoid for treating child asthma

目的探讨冬病夏治三伏贴联合吸入糖皮质激素治疗儿童哮喘的疗效。方法选择以首次诊断为哮喘的患儿200例为研究对象,按照随机数字表法分为治疗组和对照组,每组100例。治疗组给予冬病夏治三伏贴联合吸入糖皮质激素,对照组给予空白贴联合吸入糖皮质激素。随访1年,分析两组患儿的治疗有效率和肺功能,以及对免疫球蛋白IgA、IgG、IgE水平的影响。结果治疗组、对照组有效率分别为91.40%、73.03%,治疗组有效率明显高于对照组(P<0.05);治疗后对照组患儿IgA、IgG、IgE水平分别为(1.24±0.07)g/L、(8.05±0.36)g/L、(83.19±5.68)IU/mL,治疗组患儿分别为(1.40±0.09)g/L、(9.42±0.41)g/L、(80.92±6.16)IU/mL,两组患儿比较差异均有统计学意义(P<0.05);治疗1年后,两组患儿肺功能第1秒用力呼气末容积(FEV1)、FEV1/用力肺活量(FVC)、呼气峰流速(PEF)均有升高,对照组FEV1、FEV1/FVC、PEF分别为(86.83±4.78)%、(90.53±3.22)%、(78.00±5.44)%,治疗组分别为(96.44±5.39)%、(95.94±5.46)%、(88.26±4.99)%,治疗组肺功能改善情况明显优于对照组,两组比较差异均有统计学意义(P<0.05)。结论冬病夏治三伏贴联合吸入糖皮质激素治疗儿童哮喘可明显提高控制水平,改善肺功能,并提高免疫球蛋白IgA、IgG水平,值得临床推广。

Objective To investigate the effect of Sanfu Stick for treating winter diseases in summer combined with inhaled glucocorticoid in treating child asthma.Methods Two hundreds children patients with initially diagnosed asthma were selected as the study subjects and divided into the treatment group and control group,100 cases for each group.The treatment group was given Sanfu Stick for treating winter diseases in summer combined with inhaled glucocorticoid,while the control group was treated with the blank stick combined with inhaled glucocorticoid.The follow-up period was one year.After that,the curative effective rate and effects on pulmonary function and immunoglobulin IgA,IgG and IgE were analyzed in the two groups.Results The effective rates were 91.40%in the treatment group and 73.03%in the control group,and the difference between the two groups was statistically significant(P<0.05).The levels of IgA,IgG and IgE after treatment in the control group were(1.24±0.07)g/L,(8.05±0.36)g/L and(83.19±5.68)IU/mL respectively,which in the treatment group were(1.40±0.09)g/L,(9.42±0.41)g/L and(80.92±6.16)IU/mL respectively,and the differences between the two groups were statistically significant(P<0.05);the levels of forced expiratory volume in one second(FEV1),FEV1/forced vital capacity(FVC)and peak expiratory flow(PEF)ater 1-year treatment in the two groups all were increased,which were(86.83±4.78)%,(90.53±3.22)%and(78.00±5.44)%in the control group and(96.44±5.39)%,(95.94±5.46)%and(88.26±4.99)%in the treatment group,the lung function improvement rate in the treatment group was significantly superior to that in the control group,and the differences between the two groups were statistically significant(P<0.05).Conclusion Sanfu Stich for treating winter diseases in summer combined with inhaled glucocorticoid in treating child asthma can significantly increase the asthma control level,improve the lung function and is worthy of clinical promotion.