急性缺血性脑卒中患者复发再入院的相关危险因素分析

Risk Factors for Recurrence and Rehospitalization in Patients with Acute Ischemic Stroke

目的:探讨急性缺血性脑卒中(Acute ischmic stroke, AIS)患者复发再入院的相关危险因素。方法:选取2015年1月-2017年3月本院收治的AIS患者293例为研究对象。回顾患者出院后1年内AIS复发再入院情况。AIS复发入院的纳入研究组,AIS未复发入院的纳入对照组。将两组患者的相关暴露因素作为研究变量进行单因素分析与Logistic回归分析。结果:293例AIS患者1年内复发再入院有48例(16.38%),复发后的死亡或残疾率为47.92%。Logistic回归分析显示年龄>70岁、依从性不佳、基础疾病控制不佳、同型半胱氨酸血症、心房颤动、饮食控制不佳、肥胖、大动脉粥样硬化、阿司匹林和/或氯吡格雷抵抗是AIS复发入院的独立危险因素(P<0.05)。结论:AIS的复发率高,复发后的残疾率、残疾程度及死亡率均明显增加。影响AIS复发的危险因素较多,应该针对性的加强预防。

Objective: To explore the risk factors of relapse and readmission in patients with acute ischemic stroke(AIS). Method: A total of 293 AIS patients admitted to our hospital from January 2015 to March 2017 were selected as the study objects. The relapse and readmission of AIS within one year after discharge were reviewed. Patients with recurrent AIS were included in the study group and those without recurrent AIS were included in the control group. Single factor analysis and logistic regression analysis were used to analyze the related exposure factors of the two groups. Result: Among 293 AIS patients, 48 cases(16.38%) had relapse and readmission within one year, and the death or disability rate was 47.92% after relapse. Logistic regression analysis showed that age over 70 years old, poor compliance, poor control of underlying diseases, homocysteinemia, atrial fibrillation, poor diet control, obesity, atherosclerosis, aspirin and/or clopidogrel resistance were independent risk factors for relapse of AIS(P<0.05). Conclusion: The recurrence rate of AIS is high, and the disability rate, disability degree and mortality rate after recurrence increased significantly. There are many risk factors for the recurrence of AIS, and targeted prevention should be strengthened.