碱化利多卡因联合左布比卡因在眼整形术中的应用

Application of Alkalinized Lidocaine Accompany With Levobupivacaine for Ocular Orthopedic Surgery

目的研究碱化利多卡因联合左布比卡因在眼整形术中的应用效果。方法本研究以2018年10月-2019年4月行眼整形术的25例患者为对象,用5%碳酸氢钠2 mL、2%利多卡因5 mL与0.1%肾上腺素1:100 000混合液对术区局部浸润麻醉,然后用0.75%左布比卡因再次浸润麻醉。用Wong-Baker面部表情疼痛量表(Wong-Baker faces pain rating scale,WBS)进行疼痛评价,记录推注麻药时、手术结束时患者的WBS评分。统计采用单组样本的t检验,以P <0.05为差异具有统计学意义。结果推注麻药浸润时的WBS评分为(1.77±0.65)分,基本表现为无痛或仅有痛感(P=0.00);手术结束时的WBS评分为(2.15±0.97)分,基本表现为仅有痛感或轻微疼痛(P=0.00)。结论在眼整形术中用碱化利多卡因联合左布比卡因行先后局部浸润麻醉,可有效缓解推注麻药时的疼痛感,且维持麻醉时间,使得普通眼整形术获得良好的术中无痛化效果。

Objective To evaluate the use of alkalinized lidocaine accompany with levobupivacaine for ocular orthopedic surgery. Methods 25 patients underwent ocular orthopedic surgeries from October 2018 to April 2019 were elected as the objectives. A combination of 2 mL 5% sodium bicarbonate, 5 mL 2% lidocaine with 1:100 000 0.1% epinephrine was injected in the surgical area for local anesthesia. And 0.75% levobupivacaine was then injected in the surgical area again. Wong-Baker faces pain rating scale(WBS) was used to evaluate patients’ pain. The WBS score was recorded during injection of anesthetic and when surgeries were finished. One sample t-test was used to analyze the records, and P < 0.05 was considered the difference was statistically significant. Results During injection of anesthetic, the WBS score was(1.77±0.65) points, patients feel no pain or just tiny pain(P =0.00);when surgeries were finished, the WBS score was(2.15±0.97) points, patients feel tiny pain or little pain(P =0.00). Conclusion The successive local infiltration of alkalinized lidocaine and levobupivacaine in ocular orthopedic surgery could ease the pain effectively during injection of anesthetic, and maintain anesthesia, which provided fine effect of painless in ordinary ocular orthopedic surgeries.