白头翁中三萜皂苷类成分的药理研究进展

Research Progress on Pharmacological Activities of Triterpenoid Saponins from Pulsatilla chinensis (Bunge) Regel

白头翁是一味用于治疗热毒血痢、温疟寒热、鼻衄、血痔的中药,其主要成分为五环三萜皂苷类,分属于齐墩果烷型和羽扇豆烷型。研究表明,白头翁三萜皂苷具有多种药理活性,包括抗肿瘤、抗炎、抗氧化、抗病毒、抗血吸虫、增强免疫等药理作用。该文综述白头翁三萜皂苷类成分的药理研究进展。

Pulsatilla chinensis(Bunge) Regel is a traditional Chinese medicine used for the treatment of heat toxic blood stasis,warm-type malaria fever,nasal hemorrhage and blood stasis.Its main components are triterpenoid saponins,which are classified into oleanane and lupin type.Studies have shown that triterpenoid saponins from Pulsatilla chinensis has anti-tumor,anti-inflammatory,anti-oxidation,anti-viral,anti-schistosomiasis,enhancing immunity,and other pharmacological effects.This article reviews the recent research progress of pharmacological activities of tri terpenoid saponins from Pulsatilla chinensis.